It has always become a burden for most people when taking medication is the task at hand. It is not a big deal, after all, just a step to getting better. We can understand that the issue is not with the medication or medications but the idea of taking so many medications at once. There are no two ways to achieve therapy in some conditions except that you take a combination of drugs. By doing so, you can eventually rest assured of a positive outcome. It is not coincidental that most times, combination therapy is the best for the most challenging conditions.

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Ziverdo Kit and Virus

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Just like a thief in the night, Covid-19 struck the world without any prior notice, and the outbreak of this pandemic has done a lot than anyone could predict in the year 2020. Most of the affected countries suffered economically due to different lockdown phases declared in other countries of the world. The novel coronavirus also referred to as Covid-19, recorded the highest mortality in 2020. Scientists from different parts of the continent went into the race of getting a panacea for the coronavirus. Still, surprisingly, no anti-viral drug was useful in dealing with the novel virus.

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There were different suggestions of what could help in dealing with the novel virus. Some suggested ginger, vitamin c, zinc tablet as possible agents to prevent individuals from contracting the virus. Most professionals advised wearing a face mask, washing hands, maintaining social distance as the best bet when the mortality was at its peak, and other precautionary methods to reduce the virus's transmission. They suggested several drugs for arresting the novel coronavirus, but most did not break through the clinical trial.

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The Ziverdo Kit

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Ziverdo kit (Zinc, Ivermectin, and Doxycycline) is a triple combination of active drugs at their effective doses. You might wonder why you have a supplement like a zinc tablet, an anti-parasitic agent, and an antibiotic in a kit. Well, it is a matter of research, and you can be sure that the best would be what the FDA would approve.

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• Ivermectin, one of the Ziverdo kit constituents, has been an agent employed to treat several parasitic infections. It is indicated for use at the appropriate dosage, but safety at a higher dosage has not been established. Some have reported visual defects at higher doses. You may be curious enough to ask the benefit you stand to gain from the triple therapy of the Ziverdo kit. Yes, it does attack organisms of which makes it an excellent anti-viral agent. Ziverdo kit has an impressive efficacy on viruses, and this makes it logical for its use in Dengue, Yellow fever, sindbis virus, and the SARS-COV-2.  Ivermectin usually comes in a dose of 3-6mg, but in the Ziverdo kit,  the dose is increased to 12mg dispersible tablet for efficacy.

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• Zinc is another essential drug in the triple combination, which has been rightly referred to as a supplement; zinc tablet has been used in different conditions such as diarrhea for reducing bowel movement. You might begin to wonder how that has to do with the coronavirus. Yes, zinc tablet has a significance at a higher dose. It is employed at a lower dose in diarrhea cases, especially for babies who have to take a Zinc tablet of 20mg daily. Zinc is an excellent immune booster at a higher dose and has been recommended as a dietary supplement but not at an amount higher than the recommended dietary intake. The kit has Zinc acetate, which is equivalent to 50mg elemental zinc.  

 

• Doxycycline is a well-known drug used for several bacterial infections. Its use has benefited individuals who suffer viral infections due to doxycycline activity on RNA viruses. One of the reasons why the triple therapy of the Ziverdo kit is relevant is the anti-inflammatory activity of doxycycline. One of the most life-threatening symptoms of Covid-19 is hyper-inflammation of the airways, which is common among non-survivors of the Covid-19 illness. Ziverdo kit has 100mg of doxycycline, which is the standard dose of the drug.

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Ziverdo kit and other conditions

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Aside from the Covid-19 illness, other conditions that the Ziverdo kit has found relevant are Onchocerciasis, Lymphatic filariasis, and other parasitic infections. The Ivermectin content of the kit allows it to destroy parasites. Before Covid-19, the world has fought against river blindness, also known as Onchocerciasis, which is peculiar to rural communities. Luckily ivermectin, one of the Ziverdo kit constituents, won the war and extended to several other parasitic infections both internally and externally.

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Who can tolerate the Ziverdo Kit?

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For combination products, one has to be more careful due to different active ingredients. If you are hypersensitive to any active ingredient, you have to stay away from the drug. One of the crucial questions that most people ask is how suitable drugs are for pregnant women and vulnerable ones. The Ziverdo kit is contraindicated in pregnant women and children with less than 15kg body weight. However, there is no enough evidence supporting usage in lactating mothers.

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Side effects to expect when taking the Kit

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As we all know, no drug exists without side effects, except that it does not manifest in specific individuals. Some of the side effects to expect are:

 

• Pruritis

• Nausea

• Vomiting

• Rash

• Fever

• Blurred vision

• Diarrhea

• Lymphadenopathy

• Headache

• Dizziness